Samaneh Abbasi

Abadan Faculty of Medical Science, Abadan, Iran

[ 1 ] - Developing oncolytic Herpes simplex virus type 1 through UL39 knockout by CRISPR-Cas9

Objective(s): Oncolytic Herpes simplex virus type 1 (HSV-1) has emerged as a promising strategy for cancer therapy. However, development of novel oncolytic mutants has remained a major challenge owing to low efficiency of conventional genome editing methods. Recently, CRISPR-Cas9 has revolutionized genome editing.Materials and Methods: I...

[ 2 ] - Comparison of the effect of COVID-19 pandemic on the vaccination status of children in years of 2019 and 2020 in Abadan health centers, Iran

Background: Due to the great importance of maintaining vaccination coverage in children, this study examined the delay in vaccination at birth, 2, 4, and 6 months, which has recently decreased due to the COVID-19 pandemic. Methods: This cross-sectional study was performed on 213 children in 2 groups in Abadan, Iran in 2020. The children who were born from 21 March to 22 September in the years o...

[ 3 ] - The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relatio...