Rahmani, M.R.

Rafsanjan University of Medical Sciences

[ 1 ] - The Protective Effect of Carvacrol and Thymol as Main Polyphenolic Compounds of Thyme on Some Biologic Systems in Disease Condition: A Narrative Review

Thyme plant is a member of the mint family that is considered as an aromatic perennial evergreen medical herb. Carvacrol and thymol are known as two important phenolic compounds of thyme plant. Carvacrol and thymol have been identified as antioxidant, anti-oxidative and anti-inflammatory substances. Also, the neuroprotective, hepatoprotective and renoprotective effects of these polyphenolic com...

[ 2 ] - The Effect of Epigallocatechin gallate on Morphine Induced Working Memory Defects in Rats: An Experimental Study

Background and Objectives: Chronic morphine use leads to structural changes in the brain. Some studies have shown the antioxidant and neuroprotective effects of Epigallocatechin gallate (EGCG) as a main polyphenol of green tea. Therefore, the aim of this study was to investigate the effect of EGCG on working memory in morphine-treated rats. Materials and Methods: In this experimental study, 32...

[ 3 ] - Effect of Hypothermia by JZL-184 on Muscle Strength and Sensory-Motor Dysfunction in Permanent Middle Cerebral Artery Ischemia Model in Male Mice

Introduction: Currently, there is no effective and comprehensive treatment for ischemic stroke. There is strong clinical evidence for the benefits of hypothermia in neuroprotection. Therefore, the present study aimed to determine the effect of mild non-invasive hypothermia by JZL-184 on behavioral improvement in stroke rats. Methods: This study was performed on 5 groups of male mice weighing 2...

[ 4 ] - Effect of Troxerotin on permanent cerebral ischemia in male mice

Introduction: Stroke is a neurological disease and one of the leading causes of death all over the world. It is also an important cause of disability in people over age over 65. It may be possible to reduce the incidence of cerebral ischemia using antioxidants, followed by inhibition of oxidative and inflammatory mechanisms. Troxerutin is a natural bioflavonoid with antioxidant and anti-inflamm...

[ 5 ] - The Oleuropein Effect on Neurotrophic Factor Expression Level in Hippocampal Tissue and Memory Defect Induced by Morphine in Male Rats: An Experimental Study

Background and Objectives: Taking morphine can cause damage to the hippocampus. Oleuropein has a protective effect on brain neurons. The aim of this study was to determine the effect of oleuropein on brain-derived neurotrophic factor (BDNF) protein expression level in hippocampal tissue and memory defect induced by morphine in rats. Materials and Methods: In this experimental study, 40 male Wi...