Firoozeh Piroozmand

[ 1 ] - Biochemical and computational study of an alginate lyase produced by Pseudomonas aeruginosa strain S21

Objective(s): Alginates play a key role in mucoid Pseudomonas aeruginosa colonization, biofilm formation, and driving out of cationic antibiotics. P. aeruginosa alginate lyase (AlgL) is a periplasmic enzyme that is necessary for alginate synthesis and secretion. It also has a role in depolymerization of alginates. Using AlgLs in cystic fibrosis patients along with anti...