Israel Oghenevwodoko Okoro
Department of Biochemistry, Delta State University, Abraka, Delta State, Nigeria.
[ 1 ] - Anti-Oxidant and Hepatoprotective Effects of Senecio biafrae on CCl4-induced Liver Damage in Rats
Background: The present study was performed to explore whether the aqueous extract of Senecio biafrae (S. biafrae) roots provide any in vivo protective activity against carbon tetrachloride (CCl4)-induced hepatotoxicity in male albino rats. Methods: Rats (150-200 grams) were grouped into five groups (A-E) of six rats each and were treated orally for twelve days with 72 hourly administration ...
[ 2 ] - Effects of Extraction Solvents on the Antioxidant and Phytochemical Activities of Manihot Esculenta Leaves
Background: Plants contain diverse phytochemicals with different solubility levels, depending on their molecular charges and polarity. This study was conducted to examine the effects of three extraction solvents in their pure and aqueous forms: absolute petroleum ether, acetone and ethanol on the phytochemical profile and antioxidant activities of Manihot esculenta leaves extracts. Methods: Th...
[ 3 ] - Two Extracts from Manihot esculenta Leaves Efficiently Inhibit α-Glucosidase and α-Amylase: A new approach for the management of diabetes
Background: In Nigeria, the leaves of Manihot esculenta (Crantz) are eaten as vegetables. The leaves are rich in phytochemicals, valuable and natural sources of antioxidants, and are highly useful for human health and disease prevention. This study was aimed to evaluate the in vitro inhibitory effects of two extracts derived from the plant leaves on α-glucosidase and α-amylase. The total flavon...
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