somaye kouhestani

[ 1 ] - The Effect of Intrahippocampal Injection of Insulin-like Growth Factor-1 on Morphine-Induced Amnesia in Wistar Rats

Background: Morphine is wildly used as a painkiller in clinics, but causes several side effects such as hyperalgesia, depression and more notably amnesia. Here, we assumed that insulin-like Growth Factor-1 (IGF-1) as a peptide with widespread distribution of receptors in brain regions, especially hippocampus, might be capable to alleviate morphine-induced amnesia. Meth...