Deepanjan Dutta
Department of Pharmaceutical sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India
[ 1 ] - FABRICATION AND EVALUATION OF PHYSICALLY CROSSLINKED STIMULI SENSITIVE POLYMERIC BLEND OF PVA-GELATIN AS DRUG DELIVERY SYSTEM BY FREEZE THAW CYCLES
Vacuum dried Metronidazole hydrochloride (MTZ) loaded Crosslinked polymeric blend of Poly(vinyl)alcohol (PVA) and Gelatin(GE) in different ratios by 30 freeze/thaw cycles (FTC) tested for stimuli sensitivity and crosslinking at various pH, temperature, ionic concentration and oscillatory test along with dye absorption test showed maximum swelling in alkaline pH and decreased swelling with incre...
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