Aleksandra Ignasiak
Chair and Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, 6th Grunwaldzka Street, 60-780 Poznan, Poland.
[ 1 ] - Does Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?
In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requires stabilization to ensure safety of its use. The studied CIL/PVP formulations were prepared by ...
[ 2 ] - Does Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?
In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requires stabilization to ensure safety of its use. The studied CIL/PVP formulations were prepared by ...
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