Mehmet Tarakçıoğlu

Department of Biochemistry, Medical Faculty, Gaziantep University, Gaziantep, Turkey

[ 1 ] - Idarubicin-bromelain combination sensitizes cancer cells to conventional chemotherapy

Objective(s): The primary cytotoxic effects of anticancer drugs like idarubicin, a chemotherapeutic agent, are not limited to neoplastic cells; they also produce similar effects in normal cells. In this study, we hypothesized that the combination of idarubicin-bromelain could make cancer cells more susceptible to cytotoxicity and genotoxicity.Material...

[ 2 ] - Improvement of cognitive deficit of curcumin on scopolamine-induced Alzheimer’s disease models

Background: It has been suggested that curcumin may be useful in diseases with cognitive dysfunction because it slows the progression and leads to the improvement of cognitive functions. In this study, the protective effects of curcumin on scopolamine-induced rat models of cognitive impairment were evaluated. Methods: 21 male Wistar Albino rats, 1 year old, 200±25 grams, were included in the s...