Valadan, Reza
Assistant Professor, Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Construction of the Recombinant Plasmid Expressing AID under the Control of Temperature-sensitive Promoter of Bacteriophage Lambda
Background and purpose: Activation-induced cytidine deaminase (AID) is a B-cell specific enzyme responsible for somatic hypermutation (SHM) and class switch recombination (CSR) of antibody genes within the B-cell follicle of peripheral lymphoid organs. Ectopic overexpression of the enzyme leads to mutations in non-B cells and Escherichia coli (E.coli) genes. However, induction of mutations in E...
نویسندگان همکار