Samaneh Arab
Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
[ 1 ] - Blockade of Hypoxia: The Impact on Tumor Growth in an Experimental Tumor Model
Background: Tumor microenvironment is an active factor participating in immunoregulation, thereby preventing immunosurveillance and limiting the efficacy of anticancer therapies. Hypoxia as a major characteristic of solid tumors causes the expression of Hypoxia-Inducible Factor-1α (HIF-1α). This is a transcription factor that mediates hypoxic responses of tumor cells and involves in the express...
[ 2 ] - Effects of Dendritic Cell Vaccine Activated with Components of Lieshmania Major on Tumor Specific Response
Background: Dendritic cells (DCs) contribute essentially to the outset and course of immune responses. So in patients with malignancy, there have been considerable interests in use of these cells in different interventions. Objective: To evaluate the impact of Leishmania major’s components on DC maturation and their use as a therapeutic agent against t...
[ 3 ] - Relationship between the history of kidney disease, clinical findings, hospitalization duration, and mortality in COVID-19 patients
Introduction: One of the most critical conditions in the world today is coronavirus (COVID-19). The rapid and unexpected incidence of the disease in various communities has been raised many concerns. Although the respiratory and immune systems are the main targets of COVID-19, acute kidney damage and protein excretion in the urine have also been reported. Managing the disease is even more chall...
نویسندگان همکار