MOHAMMAD MEHDIPOUR

Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

[ 1 ] - Inhibitory effect of concomitant administration of Zataria multiflora Boiss. against oxidative damage-induced by sub-acute exposure to arsenic in rats

To evaluate the protective effect of Zataria multiflora boiss. (Zm) extract against arsenic-induced oxidative damage in rats. Rats were orally treated with various doses of Zm (200, 400, and 600 mg/kg) and sodium arsenite (5.5 mg/ kg), alone or in combination, once daily for 30 consecutive days. Twenty-four hours after the last dose, rats were euthanized, and biochemical studies were conducted ...

[ 2 ] - Malathion-increased Hepatotoxicity in Diabetic Rats

Background: Malathion (MT), an organophosphorus pesticide, induces hepatotoxicity and is associated with hyperglycemia and the development of diabetes mellitus.  Objectives: This study was aimed to evaluate the effects of sub-acute exposure to sub-lethal dose of MT in the liver of diabetic rats.  Methods: Non-diabetic and streptozotocin-induced diabetic rats received MT at a dose of 150 mg/kg...