غریب‌دوست, فرهاد

[ 1 ] - بررسی میزان بیان ژن‌های Fas و Apaf-1 در فیبروبلاست‌های پوست بیماران مبتلا به اﺳﮑﻠﺮوز ﺳﯿﺴﺘﻤﯿﮏ

Background: Systemic sclerosis (SSc) is an autoimmune rheumatic connective tissue disease. In normal wound healing process, fibroblasts are activated, proliferated and involved in tissue repair, and then removed by apoptosis. In systemic sclerosis, patient’s fibrosis occurs when fibroblasts become resistant to apoptosis and secrete a large amount of collagen and other extracellular matrixes. As...