وحید رضا یاسایی,

[ 1 ] - مونتاژ ژنها، روش جدیدی برای شناسایی جهشهایی ژنتیکی، کاربردی اساسی برای بررسی مولکولی ژنهای پیچیده مرتبط با سرطان ارثی پستان

Background : Most of the offending genes of diseases are quite big and complex with varieties of exons. Gene montage is a new technique for formation of a big linked DNA segment that could be easily detected by DNA sequencing or Denaturing High Performance Liquid Chromatography (DHPLC). Methods : Exons 2,20,23 and 24 of BRCA1 gene were linked and analyzed by DNA sequencing. Exons 2 and 20 are i...