میرزایی, منصوره
بخش پاتولوژی، بیمارستان بوعلی سینا ساری، دانشگاه علوم پزشکی مازندران
[ 1 ] - بررسی تأثیر جانشین پوستی تهیه شده از کشت همزمان کراتینوسیت و فیبروبلاست روی داربست کلاژنی در ترمیم زخم پوست موش صحرایی
Abstract Background: Considering the ineffective conventional therapeutic methods for treating different types of wounds, and because of reports of successful use of skin substitutes prepared from co-cultured keratinocytes and fibroblasts on the scaffold of collagen, this study was performed to evaluate the skin substitute on experimentally induced wounds in rats. Materials and methods: Thi...
[ 2 ] - Effects of Moderate Treadmill Exercise and Fluoxetine on Spatial Memory, Anxiety, and Positive Tunnel Cells in the Hippocampus in a Rat Model of PTSD
Background and purpose: Post-traumatic stress disorder (PTSD) is a condition that develops after experiencing major trauma. Selective serotonin reuptake inhibitors (SSRIs) are first-line treatment for PTSD. This study aimed at investigating the effects of moderate treadmill exercise and fluoxetine on anxiety, spatial memory, and positive tunnel cells in the hippocampus in a rat model of PTSD. ...
[ 3 ] - Protective Effect of Atorvastatin on Benzopyrene-Induced Hepatorenal Toxicity: A Histopathological Study
Background and purpose: Benzo[a]pyrene (BaP) is an environmental pollutant that has genotoxic and carcinogenic effects. Atorvastatin (ATV), as a lipid-lowering drug, has antioxidant, anti-inflammatory and anti-apoptotic properties. This study investigated the effects of ATV on chronic liver and kidney damage induced by BaP. Materials and methods: In this experimental study, adult female rats w...
[ 4 ] - Responsiveness to the Effect of Fluoxetine in Male and Female Rats Exposed to Single Prolonged Stress: A Behavioral, Biochemical, Molecular and Histological Study
Background: Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine are the first-line choice in patients with PTSD. Animal studies have indicated that chronic fluoxetine exposure leads to persistent behavioral changes and neuroplasticity in the hippocampal formation and cortex. Previous studies revealed that adult female rats respond differently to trauma from adult males. Here, we hav...