Lakshmana Rao Atmakuri

[ 1 ] - SYNTHESIS OF PARACETAMOL DERIVATIVES AS MANNICH BASES AND THEIR ANTIBACTERIAL ACTIVITY

Aim: A variety of Paracetamol derivatives as mannich bases were prepared through mannich reaction by reacting Paracetamol as compound containing active hydrogen, substituted benzaldehyde, morpholine as secondary amine compound and small amount of conc. HCl as catalyst. A simplistic one-pot method under mild conditions has been developed for the synthesis of all the compounds and they were chara...