Bahram Delfan
Lorestan University of Medical Sciences, Department of Physiology and Pharmacology Khorramabad, Iran.
[ 1 ] - Pixel selection by successive projections algorithm method in multivariate image analysis for a QSAR study of antimicrobial activity for cephalosporins and design new cephalosporins
Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pKa) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins. The antimicrobial activity of cephalosporins was related to their first pKa by different models. B...
[ 2 ] - Pixel selection by successive projections algorithm method in multivariate image analysis for a QSAR study of antimicrobial activity for cephalosporins and design new cephalosporins
Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pKa) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins. The antimicrobial activity of cephalosporins was related to their first pKa by different models. B...
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