Shima Mehrabadi
Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - GABA Agonists could Decrease Hyperalgesia and NO Serum Level in Morphine Tolerance Model
Several studies have demonstrated that nitric oxide (NO) is involved in hyperalgesia induced by NMDA activity in Morphine tolerance and NO synthase inhibitors can attenuate hyperalgesia in morphine tolerance. In addition, one of the possible mechanisms in morphine tolerance is reduction of GABA inhibitory effect. For this reason, we used GABA agonists (muscimol and baclofen) to investigate the ...
[ 2 ] - GABA Agonists could Decrease Hyperalgesia and NO Serum Level in Morphine Tolerance Model
Several studies have demonstrated that nitric oxide (NO) is involved in hyperalgesia induced by NMDA activity in Morphine tolerance and NO synthase inhibitors can attenuate hyperalgesia in morphine tolerance. In addition, one of the possible mechanisms in morphine tolerance is reduction of GABA inhibitory effect. For this reason, we used GABA agonists (muscimol and baclofen) to investigate the ...
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