Trishna Bal
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra-835215 , India
[ 1 ] - A Statistical Approach Towards Development and Optimization of Conventional Immediate Release Tablet of Nimorazole by Wet Granulation Technique
Till date, most of the drugs have been given in conventional immediate release dosage form. Nimorazole is an anticancer drug, used as a hypoxic radiosensitizer in patients undergoing radiotherapy and no formulation has been available in the market till now. Hence, for the purpose to develop an immediate release dosage form, a statistical optimization process has been employed to quantify the ef...
[ 2 ] - FABRICATION AND EVALUATION OF PHYSICALLY CROSSLINKED STIMULI SENSITIVE POLYMERIC BLEND OF PVA-GELATIN AS DRUG DELIVERY SYSTEM BY FREEZE THAW CYCLES
Vacuum dried Metronidazole hydrochloride (MTZ) loaded Crosslinked polymeric blend of Poly(vinyl)alcohol (PVA) and Gelatin(GE) in different ratios by 30 freeze/thaw cycles (FTC) tested for stimuli sensitivity and crosslinking at various pH, temperature, ionic concentration and oscillatory test along with dye absorption test showed maximum swelling in alkaline pH and decreased swelling with incre...
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