Jafar Khezri

Departnent of Animal Biotechnology National Institue of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

[ 1 ] - A Study on Merits and Demerits of Two Main Gene Silencing Techniques in Mice

Background: Transgenic mice are being considered as invaluable tool in biological sciences towards comprehension of the cause of the genetic diseases. Manipulated embryonic stem (ES) cells are used to produce loss-of-function mutant mice. Microinjection of manipulated ES cells into blastocoel cavity, and morula fusion are the two main techniques in producing transgenic mice. So...

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