Nariman Mosaffa

[ 1 ] - The effect of nimesulide on CoxII expression in central and peripheral immune cells (microglia and macrophage) in a rat model of neuropathic pain

Introduction: Neuropathic pain may be due to a primary insult to the peripheral or central nervous system. In this situation, Hyperalgesia and Allodynia are the results of prostaglandins and cytokines release in the spinal cord. It seems that immune cells play an importat role in the induction and maintenance of chronic pain. Compared to selective CoxII inhibitors, nimesulide, a highly select...