Hamid-Reza Bokaee

[ 1 ] - CYP2A6 genetic polymorphism and its relation to risk of smoking dependence in male Iranians

Introduction: Nicotine is the psychoactive substance responsible for establishing and maintaining smoking dependence. CYP2A6 is the primary enzyme that inactivates nicotine to cotinine .Genetic variation in CYP2A6 accounts for some of the inter-individual variability in nicotine metabolism and has been indicated to influence smoking behavior and dependence. Therefore, the aim of this study was ...