احمدنژاد, محرم

[ 1 ] - بررسی بیان پروتئین‌های P16 و DAPK در رده‌ی سلولی لوسمیک HL60 در مجاورت با آلکالوئید گیاهی

Introduction: Epigenetic changes such as promoter methylation of tumor suppressor genes (TSGs) is one of the most important mechanisms involved in the development of hematologic malignancies. Harmine is one of the Harmal-derived alkaloids with anti-proliferatory effects on leukemia cell lines. Since P16 and DAPK genes are hypermethylated in some hematologic malignancies, the current study aimed...