Rita Mulherkar

[ 1 ] - Lymphoblastoid cell lines: a continuous in vitro source of cells to study carcinogen sensitivity and DNA repair

Obtaining a continuous source of normal cells or DNA from a single individual has always been a rate limiting step in biomedical research. Availability of Lymphoblastoid cell lines (LCLs) as a surrogate for isolated or cryopreserved peripheral blood lymphocytes has substantially accelerated the process of biological investigations. LCLs can be established by in vitro infection of resting B cell...