Ali Mahdavinezhad
Research Center for Molecular Medicine, Department of Genetics and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
[ 1 ] - Evaluation of MicroRNA-99a and MicroRNA-205 Expression Levels in Bladder Cancer
Bladder cancer is the second most common cancer in the genitourinary tract, showing often recurrence and progresse into invasive states. Epigenetic changes, such as microRNA alteration are involved in bladder cancer tumorigenesis through a variety of signaling pathways. The epigenetic state depends on geographic and lifestyle conditions. The aim of this study was to investigate the expression l...
[ 2 ] - Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
Bladder cancer (BC) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. MiRNAs expression has noticeable role in bladder tumorigenesis. The purpose of this study was to assess miR-200c, miR-30b and miR-141 in tissue samples of patients with BC and healthy adjacent tissue samples and their association with muscle invasion, grade...
[ 3 ] - Diagnostic Value of Plasma Long Non-coding RNA HOTTIP as a Non-invasive Biomarker for Colorectal Cancer ( A Case- Control Study)
Long non-coding RNAs (lncRNAs) associated with various cancers, including colorectal cancer (CRC), could be collected from body fluids easily. Our aims were to determine the expression level of HOTTIP lncRNA in plasma samples of healthy individuals and CRC patients as well as their relationship with clinico-pathological characteristics of patients. First, total RNA was extracted from the plasma...
[ 4 ] - Significance of exosomes in COVID-19 pathogenesis and therapy
Exosomes are lipid bilayer-enclosed nano-sized vesicles, which carry various biomolecules including proteins, lipids, and microRNAs. SARS-CoV-2-loaded exosomes can be entered into the susceptible host cells, and transported viral components which are associated with viral particles intercellular transmission and spread of infection. Over-stimulation of the immune system followed by excessive pr...
[ 5 ] - Evaluation of miR-330-3p and BMI1 Expression in Colorectal Cancer Patients, Healthy Adjacent Tissues, and Polypoid Adenomatous Lesions
MicroRNAs (miRNAs) have emerged as essential gene expression regulators associated with human diseases such as colorectal cancer (CRC). The purpose of this study was to evaluate the expression of miR-330-3p and its target gene BMI1 in tissue samples of patients with CRC, polyp, and healthy adjacent tissue samples and their association with clinicopathological and demographic factors such as age...
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