Aghdas Dehghani

Department of Physiology,

[ 1 ] - The Role of Mas Receptor and Bradykinin on Nitric Oxide Production Response to Angiotensin 1-7 in Ovariectomized Rats Treated with Estradiol

Introduction: The angiotensin 1-7 (Ang1-7) Mas receptor (MasR) axis, bradykinin (BK) and female sex hormone are involved in releasing of vasodilatory biomarkers including Nitric Oxide (NO). We examined the role of MasR and BK on NO metabolite (nitrite) production response to Ang 1-7 infusion in ovariectomized rats treated with estradiol. Methods: A total of 48 female Wistar rats were divided i...

[ 2 ] - Role of Bradykinin and Mas Receptor Blockade in Renal Vascular Responses to Angiotensin 1-7 in Adult Female Rats

Background and purpose: Chronic kidney disease is among the common diseases in the world. Studies show that women are more protected against renal diseases compared to men. On the other hand, vasodilatory axises of renin angiotensin system (angiotensin 1-7 (Ang 1-7)- Mas receptor (MasR)), kallikrein-kinin, and nitric oxide (NO) play key roles in kidney function and circulation in females. There...

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