Soleiman Mahjoub
,Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran.
[ 1 ] - Comparison of thiobarbituric acid reacting substances and total antioxidant capacity in saliva of smokers and nonsmokers
Introduction: The aim of this study was to evaluate thiobarbituric acid reactive substances (TBARS) as lipid peroxidation marker and total antioxidant capacity(TAC) in saliva of smoker and non-smoker men. Materials & Methods: This case-control study was performed on 104 men including smoker (52) and non-smoker (52) men, referred to the Oral Medicine Department in Babol Faculty o...
[ 2 ] - Alterations in serum levels of trace element in patients with breast cancer before and after chemotherapy
Background: Breast cancer is the most common serious disease around the world. The trace elements have a vital role in the metabolism and chemotherapy may change the level of metal ions. Due to the ambiguity of the existence in this regard, the study examined the trace element serum levels in women with breast cancer before and after chemotherapy . Methods: Sixty patients were studied undergoi...
[ 3 ] - Three cycles of AC chemotherapy regimen increased oxidative stress in breast cancer patients: A clinical hint
Background: Recent studies have suggested the importance of oxidant/antioxidant status in initiation and progression of breast cancer. The aim of this study was to evaluate oxidative stress markers in breast cancer patients before and after 3 cycles of chemotherapy with adriamycin and cytoxan (AC). Also, in this study the effect of age and the stage of disease on oxidative stress markers were c...
[ 4 ] - The effect of green tea consumption on oxidative stress markers and cognitive function in patients with Alzheimer’s disease: A prospective intervention study
Background: Alzheimer’s disease (AD) is the most prevalent degenerative disorder of the brain among elderly individuals. Many studies indicate that oxidative stress is an important pathogenic factor which involves oxidizing macromolecules such as DNA, lipids, and proteins in AD. Green tea is a rich source of antioxidant compounds that can remove radical oxygen species. The purpose of this...
[ 5 ] - Altered plasma marker of oxidative DNA damage and total antioxidant capacity in patients with Alzheimer\'s disease
Background: Recent studies have shown that oxidative stress (OS) is the most important indicator in the pathogenesis of Alzheimer's disease (AD), but the results in previous studies are conflicting. This study aimed to assess the plasma levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG) as DNA oxidative damage marker and total antioxidant capacity (TAC) in patients with AD versus control group. ...
[ 6 ] - Evaluation of oxidative stress in endometriosis:A case-control study
Abstract Background: Recent studies have suggested that oxidative stress (OS) may have a contribution in the pathogenesis of endometriosis. However, the results of previous studies regarding OS in endometriosis are controversial. The objective of this study was to compare the serum levels of OS markers in endometriosis versus the control group. Methods: This case-control study was carried out...
[ 7 ] - Synthesis and optimization of Chitosan nanoparticles: Potential applications in nanomedicine and biomedical engineering
Background: Chitosan nanoparticles have become of great interest for nanomedicine, biomedical engineering and development of new therapeutic drug release systems with improved bioavailability, increased specificity and sensitivity, and reduced pharmacological toxicity. The aim of the present study is to synthesis and optimization of chitosan nanoparticles for industrial and biomedical applicati...
[ 8 ] - Pre and post chemotherapy evaluation of breast cancer patients: Biochemical approach of serum selenium and antioxidant enzymes
Backgrounds: Chemotherapy for treatment of breast cancer uses some drugs to target and destroy the cancer cells. However, most of antineoplastic treatments are non-specific and the innate cells will be damaged. In this study, the effect of Adriamycin/Cytoxan (AC) chemotherapy on status of antioxidant enzymes and Se levels in breast cancer patients was evaluated. Methods: A prospective study, i...
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