F Sadeghpour Heravi

[ 1 ] - Allelic variations between vaccine strains and circulating strains in pxtP of Bordetella pertussis in Iran

Introduction: Despite high level of vaccination against pertussis‚ whooping cough has re-emerged as a health threat, especially in infants. This could be related to expansion of Bordetella pertussis with novel alleles for virulence factors including the pertussis toxin promoter, ptxP3. Compared to ptxp1 strains‚ ptxp3 strains produce more pertussis toxin which results in immune supp...