Ehsan Akbarian
Karolinska Institutet Stockholm, Sweden.
[ 1 ] - Evaluating suppression of PGE2, PAF, and histamine synthesis and histopathological changes of bones in the membrane surrounding particulate polymethylmethacrylate in the rat tibia
Abstract Introduction: Inflammation and wear debris may be responsible for bone lysis and subsequent lost in aseptic arthroplasty. Prostaglandin E2, platelet activating factor, and histamine are important mediators of inflammatory cells. We studied histopathological changes of cement-bone interface after using specific antagonists of these mediators. Methods: Left and right tibiae...
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