Nasser Naghdi

[ 1 ] - The Effect of Ketanserin and Pirenperone Injected into the CA1 Region on Spatial Discrimination

In the present study, the effect of 5-HT2A receptor blockers in CA1 region of rat hippocampus on spatial learning was assessed in a T-maze, a spatial discrimination task. Rats were canulated bilaterally and injected daily vehicle (saline), 5-HT2A-selective antagonist, ketanserin (0.6, 1.2 or 2.4 µg/0.5 µl) and pirenperone (0.1, 0.3, 1.2 or 2.4 µg/0.5 µl) into the cannula 30 minutes before train...