Sadegh Yoosefee

Department of Neuroscience, School of Advanced Technologies in Medicine, Iran University of Medical Sciences

[ 1 ] - cAMP-Epac Pathway Stimulation Modulate Connexin-43 and MicroRNA-21 Expression in Glioma Cells

Introduction: Malignant astrocytic gliomas are the most common and lethal brain malignancies due to their refractory to the current therapies. Nowadays, molecular targeted therapy has attracted great attention in treatment of glioma. Connexin 43 (Cx43) and micro ribonucleic acid- 21(miR-21) are among molecules that are involved in glioma development and progression. These molecules showed...

[ 2 ] - Effectiveness of An Islamic Approach to Hope Therapy on Hope, Depression, and Anxiety in Comparison with Conventional Hope Therapy in Patients with Coronary Heart Disease

Background and Objective: Hope therapy is an efficient and positive psychology intervention used to treat chronic diseases. The purpose of this study was to investigate the effect of hope therapy on anxiety and depression using an Islamic approach and compare this approach with conventional hope therapy in coronary heart disease (CAD) patients. Materials and Methods: The study was conducted in...

[ 3 ] - Therapy on Self-esteem and Life Satisfaction of Patients with Coronary Artery Disease

Background and Objectives: The decreased level of self-esteem and life satisfaction is prevalent among patients with coronary artery disease (CAD). The present study aimed to investigate the effectiveness of an Islamic approach to hope therapy on the promotion of self-esteem and life satisfaction in comparison with its conventional approach in patients with CAD. Methods: The study was conducte...