Adegbuyi Oladele Aderibigbe

Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.

[ 1 ] - Protective Effects of Morin Hydrate on Acute Stress-Induced Behavioral and Biochemical Alterations in Mice

Introduction: As stress affects the brain both physiologically and chemically, researchers try to find novel anti-stress compounds with beneficial therapeutic effects. In this regard, the effect of stress and its modulation by Morin hydrate was studied using different acute models in mice. Methods: The models employed were anoxic tolerance, swimming endurance, and acute restraint test. Morin h...

[ 2 ] - Morin Hydrate ameliorates Chronic Restraint Stress-Induced Biochemical Disruption, Neuronal and Behavioral Dysfunctions in BALB/c Mice

Background: Morin hydrate (MH) is a bioflavonoid component of many fruits and vegetables. Our previous investigations demonstrated that MH confer neuroprotection in mouse models of acute restraint stress and sleep deprivation by attenuating hippocampal neuronal damage and enhancing memory. Based on these findings, our study investigated the role of MH in chronic stress-induced neuronal and bioc...