Reza Mastery Farahani

[ 1 ] - Sexual Dimorphism and Age-Related Variations of Corpus Callosum Using Magnetic Resonance Imaging

Introduction: Despite technological advances and numerous published investigations, sexual dimorphism of Corpus Callosum (CC) remains a matter of ongoing controversy. In the present study on neurologically healthy Iranian adults, we investigated the possible gender- and age-related variations in anthropometric callosal measurements.  Methods: Our sample comprised 35 male and 35 female sub...

[ 2 ] - Role of E-Learning in Teaching Anatomical Sciences

Introduction: Medical undergraduates usually understand and memorize anatomical course material with difficulty. Also, the current text books and atlases of anatomy and histology do not fulfill all the learning needs of the undergraduates. Therefore, it is necessary to consider the role of internet websites and computer programs (i.e. the role of electronic learning) in teaching....

[ 3 ] - A Case Report: Rare Communication of Ansa Cervicalis

During the past few years, researchers and practitioners have developed novel techniques, using ansa cervicalis to innervate muscles of the larynx paralyzed due to surgical procedures carried out in the chest and neck areas. During routine dissection of a middle-age male cadaver, an unusual course of the superior root of the ansa cervicalis was observed. In this case, the su...

[ 4 ] - Repressing of SOX6 and SOX9 in Situ Chondrogenic Differentiation of Rat Bone Marrow Stromal Cells

Introduction: SOX9 is a transcriptional activator which is necessary for chondrogenesis. SOX6 are closely related to DNA-binding proteins that critically enhance its function. Therefore, to carry out the growth plate chondrocyte differentiation program, SOX9 and SOX6 collaborate genomewide. Chondrocyte differentiation is also known to be promoted by glucocorticoids through unknown molecular mec...

[ 5 ] - Stable Transfection of pEGFP-N1-MOG Plasmid to Utilize in Multiple Sclerosis Gene Therapy

Introduction: Multiple sclerosis (MS) is a disease of the immune system: it attacks the myelin around the axons and leaves them exposed. Destruction of myelin weakens the electrical conduction of ions and thus leads to a lack of communication in the nervous system. Methods: In the present study, we constructed recombinant plasmid and then transformed to E. coli cell. The colonies containing...

[ 6 ] - Nandrolone decanoate administration can increase apoptosis in spermatogenesis cell lines in male rats

Introduction: Anabolic – androgenic steroids (AAS) are used at high doses by athletes for improving athletic ability, muscle mass and physical appearance. Unfortunately, the abuse of these agents has been significantly increased. It has been established that exercise and high doses of AAS may influence the hypothalamic-pituitary-gonadal axis, which can in turn affect testicular apoptosis and m...

[ 7 ] - محافظت نورون های دوپامینرژیکی به وسیله جینکولاید در بیماری پارکینسون مدل 6-هیدروکسی دوپامین

Background and purpose: Parkinson's disease (PD) is a prevalent movement disorder in elderly with progressive motor complications due to antioxidant defense system deficiency and accumulation of degraded proteins in dopaminergic neurons of midbrain. Ginkgolide is biologically active terpenic lactones as a polyphenol, with potent antioxidant and anti-inflammatory properties. The present study ai...

[ 8 ] - Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways

Trehalose, as a natural disaccharide, is known as an autophagy inducer. The neuroprotectiveeffects of trehalose in the rat model of Parkinson′s disease were the aim of the present study.Parkinson′s disease model was induced by injecting 6-hydroxydopamine (6-OHDA) in thestriatum of male Wistar rats. Apomorphine-induced behavior and substantia nigra neuronalcounts were app...

[ 9 ] - Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways

Trehalose, as a natural disaccharide, is known as an autophagy inducer. The neuroprotectiveeffects of trehalose in the rat model of Parkinson′s disease were the aim of the present study.Parkinson′s disease model was induced by injecting 6-hydroxydopamine (6-OHDA) in thestriatum of male Wistar rats. Apomorphine-induced behavior and substantia nigra neuronalcounts were app...

[ 10 ] - Effect of Adriamycin on α1β1, α1β4, and ανβ3 Expression in Rat Endometrium in Estrus Phase

Introduction: Although the effect of adriamycin, a chemical drug used to treat cancer, is known to affect gametogenesis and ovarian function, the drug’s effect on endometrial receptivity and expression of integrin genes is unclear. To fill this gap, we aimed to investigate the effect of adriamycin on the expression of integrin genes that play a role in endometrial receptivity. Methods: A total...