هاشمی, دکتر محمد
[ 1 ] - روشهای بررسی آپوپتوز
Background and Objective: Apoptosis or programmed cell death is an important process for cellular homeostasis and it can be initiated by both physiologic and pathologic stimuli. Defects in the apoptosis process may lead to serious disease such as autoimmune diseases, cancer, tumors drug resistance, and the acquired immunodeficiency syndrome (AIDS). Various methods such as cytotoxicity assay, mo...
[ 2 ] - A 40-bp Insertion/Deletion Polymorphism of Murine Double Minute2 (MDM2) Increased the Risk of Breast Cancer in Zahedan, Southeast Iran
Background: MDM2 (Murine Double Minute2) is an oncoprotein that inhibits the P53 activity. Overexpression of MDM2 gene has been reported in several human tumors. In the present study, we aimed to evaluate the impact of 40-bp insertion/deletion (ins/del) polymorphism on the promoter of MDM2 and susceptibility to breast cancer in a sample of Iranian population. Methods: This case-control study wa...
نویسندگان همکار