شبستانی‌منفرد, علی
[ 1 ] - اثر پرتوگیری طبیعی بسیار زیاد بر سلول‌های خون محیطی ساکنین مناطق با پرتوزایی طبیعی بالا در رامسر
Background and Objective : Natural radioactivity has been the subject of studies for many years. The mean of radiation doses of human from natural sources is about 2.5 mSv/year, but in some regions in the world this value is many times greater than the world mean. Ramsar, a city in Iran, is one of the most important high natural background areas of the world. According to UNSCEAR 2000 report,...
[ 2 ] - بررسی سطح سلامت ساکنین مناطق با پرتو زایی زمینه بالا و زمینه پایین در رامسر
مقدمه و هدف: رامسر در شمال ایران، بالاترین میزان پرتوزایی زمینه را در سطح جهان داراست. این پرتوزایی عمدتاً به دلیل وجود عنصر رادیواکتیو رادیوم و فرآورده های استحاله آن است که توسط چشمه های آب گرم به سطح زمین آورده می شوند. آثار دزهای کم پرتو بر سلامت انسان همچنان در هاله ای از ابهام قرار داشته و هنوز تحت بررسی های متعدد قرار دارد. هدف از این تحقیق بررسی وضعیت سلامت ساکنین مناطق با پرتوزایی زمینه...
[ 3 ] - Radioadaptive Response in Human Lymphocyte Cells
The adaptive response (AR) is a phenomenon by which cells exposure to sublethal doses of DNA-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (CT), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (CR). The adaptive response (AR) induced by radiation in human lymphocyte...
[ 4 ] - Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our ...
[ 5 ] - Estimation of external natural background gamma ray doses to the population of Caspian coastal provinces in North of Iran
Background: The effect of natural background radiation on health is still controversial. However, it is clear that it depends on the dose received by the population. The estimation of external natural background gamma rays received by the population of Caspian coastal provinces in the northern part of Iran was the main goal of this study. Materials and Methods: Gamma rays was measured ...
[ 6 ] - Repeat analysis program in radiology departments in Mazandaran province- Iran Impact on population radiation dose
Background: The rejected films in radiography may be responsible for an unnecessary increase in the radiation dose to the population. The effective dose to population is a very important factor in estimation of stochastic risk in radiology. The main goal of this study was to determine the effective dose to members of the public due to rejected films in diagnostic radiology departments in the No...
[ 7 ] - Can previous thyroid scan induce cytogenetic radioadaptive response in patients treated by radioiodine for hyperthyroidism?
Background: Induction of radioadaptive responses in cells pretreated with a low dose radiation before exposure to a high dose is well documented by many investigators. The aim of this study is to determine the frequency of chromosomal aberration in peripheral blood lymphocytes of patients treated by radioiodine (131I) for hyperthyroidism, with or without previous thyroid scan with 99mTc. Materi...
[ 8 ] - فاکتورهای پیش بینی کننده میزان حساسیت پرتویی در رادیوتراپی فردی
سابقه و هدف: دوز پرتویی در رادیوتراپی بیماران براساس نوع و گرید تومور و درمانهای جانبی در غالب پروتکل های آنکولوژی متفاوت است. از طرفی برخی فاکتورهای پیش بینی کننده حساسیت پرتویی فردی در تجویز دوز در رژیم های درمانی کنونی در نظر گرفته نمی شود که با رعایت رادیوتراپی فردی می توان دوز پرتو را با رعایت کنترل تومور کاهش داد تا عوارض جانبی کاهش یابد .در این مطالعه مهمترین فاکتورهای موثر در پیش بینی ح...
[ 9 ] - پرتوزایی طبیعی، تطبیق و هورمسیس پرتویی
خلاصه پرتوزایی طبیعی سالهاست که مورد توجه دانشمندان قرار گرفته است. معمولاً سطح پرتوگیری انسان از منابع مختلف طبیعی حدود 5/2 میلی سیورت در سال است. این میزان در برخی از مناطق دنیا، بسیار بیشتر است. یکی از مهمترین این نقاط، رامسر است که دارای بیشترین سطح پرتوزایی طبیعی در مناطق مسکونی تمام زمین است. پرتوزایی زمینه یک تابش یونیزاسیون (Ionizing Radiation) است که در محیط طبیعت وجود دارد و می‌تواند ...
[ 10 ] - Combined Effect of Iodine Contrast Media, Cisplatin and External Beam Radiotherapy on Anaplastic Thyroid Cancer Cells
Introduction: The current study investigated the combination of high Z atoms (iodine-, platinium-based drugs) with using low energy irradiation (120kvp) in Anaplastic Thyroid cancer cells.Materials and Methods: For this purpose, eight groups were designed: control (CNT), different concentrations of Iodine contrast media (ICM), irradiation with various doses, Cis-platin (CDDP) with different c...
[ 11 ] - Radioprotective Effects of Sulfur-containing Mineral Water of Ramsar Hot Spring with High Natural Background Radiation on Mouse Bone Marrow Cells
Background: We intend to study the inhibitory effect of sulfur compound in Ramsar hot spring mineral on tumor-genesis ability of high natural background radiation. Objective: The radioprotective effect of sulfur compounds was previously shown on radiation-induced chromosomal aberration, micronuclei in mouse bone marrow cells and human peripheral lymphocyte. Ramsar is known for having the highe...
[ 12 ] - Oral Administration of Vitamin C, Cimetidine and Famotidine on Micronuclei Induced by Low Dose Radiation in Mouse Bone Marrow Cells
 Background: In many studies, chemicals and natural materials were tested to reduce the harmful effects of radiation. It is known that Famotidine and vitamin C reduce DNA damage.Objective: The aim of this study was to evaluate the radioprotective effect of vitamin C, Cimetidine and Famotidine on gamma-radiation-induced damage on mouse bone marrow. Methods: Six-to-seven week male NMRI mice (28...
[ 13 ] - Evaluation of Radiation Exposure to Staff and Environment Dose from [18F]-FDG in PET/CT and Cyclotron Center using Thermoluminescent Dosimetry
Background: PET/CT imaging using [18F]-FDG is utilized in clinical oncology for tumor detecting, staging and responding to therapy procedures. Essential consideration must be taken for radiation staff due to high gamma radiation in PET/CT and cyclotron center. The aim of this study was to assess the staff exposure regarding whole body and organ dose and to evaluate environment dose in PET/CT an...
[ 14 ] - Changes in the Radiation Toxicity of Human Lymphoblastic T-cell Line (Jurkat) by a Common Pesticide: Diazinon
Background: Diazinon is one of the most common pesticides in the world playing a similar role to radiation and it could cause DNA breaks and genetic effects.Objective: In this study, radiosensitivity of a lymphoblastic cell line pretreated by Diazinon was investigated. Material and Methods: In this case-control study, the human lymphoblastic T-cell line was divided into 6 groups bas...
[ 15 ] - Developing a Mobile Phone Application for Common Radiotherapy Calculations
Accuracy of the radiotherapy requires some routine quality control and dosimetry calculations, which would be done by radiotherapy physicists. Due to the increasing use of computers and simulation software in medical science, as well as trends indicating its continued growth, this study aims to develop a new smart-phone application to perform common radiotherapy-related calculations. Computatio...
[ 16 ] - The assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations
Background: Compared to past decades, humans are exposed to rapidly increasing levels of radiofrequency electromagnetic radiations (RF-EMF). Despite numerous studies, the biological effects of human exposure to different levels of RF-EMF are not fully understood, yet. This study aimed to evaluate the bioeffects of exposure to "900/1800 MHz" and “2.4 GHz" RF-EMFs, and x-rays as well as their pot...