روح بخش, علی
گروه فارماکولوژی، مرکز تحقیقات علوم دارویی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
[ 1 ] - بررسی اثر تزریق تک‌دوز مرفین بر شاخص‌های خستگی عضلانی در موش‌های صحرایی نر
Background and Aim: Endogenous opioids and addictive opiate drugs change many body functions. . Previous studies have referred to the effects of morphine on smooth and pulmonary muscles ., but the effects of opioids on skeletal muscles is not known well. Thus, the current study aimed at assessing the effect of a single dose of morphine on muscle fatigue in male rats. Materials and Meth...
[ 2 ] - اثر تزریق داخل بطنی آگونیست و آنتاگونیست اختصاصی گیرنده GABAc بر رفتارهای شبه اضطراب در موش‌های صحرایی نر
Background and Objective: The Gamma Amino Butyric Acid (GABA), has three receptors: A, B and C in the body. GABAc receptors play an important role in process of vision, however, their role in other physiological processes yet to be identified. The aim of this study was to evaluate the effect of specific drugs for GABAC agonist and antagonist on anxiety, in male rats. Materials and Methods: In ...
[ 3 ] - Effects of Dimethyl Sulfoxide on Neuronal Response Characteristics in Deep Layers of Rat Barrel Cortex
Introduction: Dimethyl sulfoxide (DMSO) is a chemical often used as a solvent for waterinsoluble drugs. In this study, we evaluated the effect of intracerebroventricular (ICV) administration of DMSO on neural response characteristics (in 1200–1500 μm depth) of the rat barrel cortex. Methods: DMSO solution was prepared in 10% v/v concentration and injected into the later...
[ 4 ] - Vitex Agnus Castus Extract Improves Learning and Memory and Increases the Transcription of Estrogen Receptor α in Hippocampus of Ovariectomized Rats
Introduction: Lower level of estrogen hormone is considered as an important factor for loss of learning and memory in postmenopausal women. Although estrogen replacement therapy is used for compensation, but long-term usage of estrogen is associated with a higher risk of hormonedependent cancers. Phytoestrogens, due to fewer side effects, have been proposed to prevent menopause-related co...
[ 5 ] - Paraquat-induced systemic inflammation and increased oxidative markers in rats improved by Zataria multiflora extract and carvacrol
Objective: Paraquat (PQ) is a herbicide which induces oxidative stress and inflammation. Anti-inflammatory and anti-oxidant effects were shown for Zataria multiflora (Z. multiflora) and carvacrol previously. The effects of Z. multiflora hydroalcoholic extract and carvacrol on systemic inflammation and oxidative stressinduced by inhaled PQ were examine...
نویسندگان همکار