اکبری, جعفر

[ 1 ] - بررسی تأثیر اندازه ذره ای دارو و پلیمر HPMC K15M بر میزان رهش تئوفیلین از ماتریکس های پلیمری

Background and purpose: One of the methods of preparing controlled-release dosage forms is the incorporation of drug in a matrix containing a hydrophilic rate-controlling polymer. Drug-polymer ratio, drug particle size and HPMC particle size have been identified as modifiers of drug release. This study evaluated the relationship and influence of formulation factors such as drug-HPMC ratio and p...