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علوم پزشکی مازندران

[ 1 ] - سطح سرمی هورمون گرلین در دختران مبتلا به بلوغ زودرس واقعی قبل و حین درمان با آگونیست‌های GnRH و رابطه آن با چاقی

Background and purpose: The precocious puberty in girls can have some adverse effects such as growth stoppage and subsequent short stature in comparison with predicted final adult height. GnRH agonists are now considered the treatment of choice for CPP. One of the side effects of these drugs is increased appetite and consequent obesity. During puberty a progressive reduction in the level of ghr...

[ 2 ] - گزارش یک مورد بیماری کاناوان در یک پسر بچه 5/2 ساله

Canavan disease is an autosomal recessive leukodystrophy due to accumulation of N-acetyl aspartic acid (NAA) in brain, cerebrospinal fluid (CSF), and urine characterized by early onset developmental delay, initial hypotonia progressing to hypertonia, sleep disturbance and macrocephaly. Brain magnetic resonance imaging (MRI) shows white-matter changes. The best method for diagnosis is determined...

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