زارع, زهره
استادیار، گروه فیزیولوژی و فارماکولوژی، مرکز تحقیقات بیولوژی سلولی و مولکولی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران
[ 1 ] - ترکیبات ارگانوفسفره و سیستم گابائرژیک مغز
Organophosphorus (OP) compounds are cholinesterase inhibitors widely used as pesticides in agriculture and nerve agents in battlefields. Exposure to these compounds leads to accumulation of acetylcholine at cholinergic synapses and overstimulation of muscarinic and nicotinic receptors by inhibiting the enzyme acetylcholinesterase. Seizure activity is one of the major manifestations of OP poison...
[ 2 ] - مطالعه آسیب بافتی دی (2- اتیل هگزیل) فتالات (DEHP) بر بیضه موش سوری
Background and purpose: Di-(2-ethylhexyl) phthalate (DËHP) is plasticizer used commonly in a variety of polyvinyl chloride- based consumable products. The purpose of this study was to evaluate the effects of DËHP on body weight, testis weight, seminiferous tubular diameter, seminiferous epithelium height, seminiferous lumen diameter, number of sertoli cells and round spermatids per seminifero...
[ 3 ] - Cognitive Function and Hippocampal Glutathione and Malondialdehyde Levels in Paraoxon-intoxicated Rats
Background and purpose: Exposure to organophosphorus (OP) compounds may contribute to an increased risk of cognitive impairments and induction of oxidative stress. The present study was designed to evaluate the effects of exposure to paraoxon (the active metabolite of insecticide parathion) on cognitive function and oxidative stress biomarkers. Materials and methods: Adult male Wistar rats (n=...
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