هادی ندوشن, حسین

دانشگاه علوم پزشکی و بهداشتی درمانی شهید صدوقی یزد، یزد

[ 1 ] - بررسی عصاره متانولی برخی گیاهان بومی استان یزد بر تکثیر سلول‌های تک‌هسته‌ای خون محیطی و ترشح اینترلوکین چهار

Introduction: Echinops ilicifolius, Echinops jesdianus, Echinops ceratophorus and Echinops lasiolepis are defined as native plants of Yazd that their immunomedulatory effects have not been studied yet. The aim of this study was to determine the effect of different concentrations of these plants on peripheral blood mononuclear cells(PBMCs) proliferation and interleukin(IL)-4 secretions. method...

[ 2 ] - بررسی سایتوکاین‌های سلول‌های Th1 و TH17 تحریک شده در محیط کشت سلولی در زنان مبتلا به سقط مکررخود به خودی

Introduction: Various immunological abnormalities have been reported in women with RSA of unknown aetiologies including autoimmune abnormalities and increased cellular immunity such as elevated natural killer (NK) , Th1 and Th17 cell levels. Th17 and Th1 cells play a central role during inflammation. Th1 cells product cytokines IFN-γ, IL-2 and Th17 cells mainly cytokines IL-17A, F, IL-22. The a...

[ 3 ] - بررسی نگرش اعضای هیأت علمی زن دانشگاه علوم پزشکی شهید صدوقی یزد در مورد موانع ارتقاء آنان به پست های مدیریتی

   Introduction: In spite of equal contribution of female and male faculty members to knowledge and expertise production, there is no equal access to managerial posts. The purpose of this study was to determine the present attitudes of female faculty towards the barriers to their promotion to managerial posts in ShahidSadoughi University of Medical Sciences (SSUMS ).   Methods: This cross-secti...

[ 4 ] - The Effect of Echinops Lasiolepis Extracts, Native Plant of Yazd Province, on Peripheral Blood Mononuclear Cell Proliferation and IFN-γ Secretion

Background and Aims: The present study was performed to investigate the effect of Echinops lasiolepis extract on peripheral blood mononuclear cells (PBMCs) proliferation and interferon (IFN)-&gamma secretion. Materials and Methods: PBMCs were obtained from three healthy volunteers and cultured in presence of Echinops lasiolepis methanol extract in different concentrations of 0.1, 1, 10, 100 ...

[ 5 ] - Physiological and Pathological Roles for MicroRNAs: Implications for Immunity Complications

MicroRNAs (miRNAs) are small non-coding regulatory RNAs molecules with a size of approximately 22 nucleotides that are implicated in regulating gene expression at the post-transcriptional regulatory levels. Inflammatory disorders especially autoimmune diseases (ADs) occur from an abnormal immune response of body against cells of their own specific tissues or multiple organ systems leading to ch...

[ 6 ] - Comparison of Wright Agglutination Test and ELISA in Diagnosis of Brucellosis

Abstract Background and Objective: In our country, the Wright test routinely is used for diagnosing brucellosis. Because of its low sensitivity, the range of false-negative results is high. Therefore, we aimed at comparing Wright and ELISA in the people suspected brucellosis. Material and Methods: The results of Wright, 2ME, Coombs Wright tests were compared with Anti-Brucella IgG, Anti-Bru...

[ 7 ] - The Efficacy and Safety of a High Dose of Vitamin D in Mothers with Gestational Diabetes Mellitus: A Randomized Controlled Clinical Trial

Background: During pregnancy and lactation outstanding changes occur in mother’s vitamin D metabolism. This study was carried out to evaluate the efficacy of 300,000 IU vitamin D given intramuscularly on body status in new cases of gestational diabetes mellitus (GDM). Methods: This is a randomized clinical trial with the follow-up period of 3 months. Totally 45 participants were randoml...

[ 8 ] - EVALUATION OF SERUM CHITINASE-3 LIKE 1 PROTEIN AND C-REACTIVE PROTEIN LEVELS IN TYPE 2 DIABETES MELLITUS WITH CORONARY ARTERY DISEASE COMPARED TO DIABETIC AND HEALTHY CONTROL

Background: Diabetes mellitus, which is associated with elevated blood glucose, lipids and liver enzymes, may results in alterations in the production of inflammatory cytokines, including chitinase-3-like protein 1 (YKL-40) and high-sensitivity C-reactive protein (hs-CRP), which induce and promote complications of diabetes such as atherosclerosis.The aim of this study was to evaluate the serum ...