دربندی, نیلوفر
دانشگاه اراک
[ 1 ] - مقایسه اثرات حاد و مزمن متفورمین بر شاخصهای استرس اکسیداتیو در سرم رت‌های نر آلزایمری شده با استرپتوزوتوسین
Introduction: Studies have indicated that metformine has different effects on learning and memory. In this study, both acute and chronic therapeutic effects of metformin on memory retrieval and some serum oxidative stress factors in Streptozotocin -induced Alzheimeric male rats were investigated. Methods: In this experimental study, 48 rats were divided into six groups (n=8) as follows: saline...
[ 3 ] - اثر عصاره آبی-الکلی دانه زغال اخته بر بازخوانی حافظه و برخی پارامترهای سرم در موشهای سوری نر آلزایمری شده
هدف: در تحقیق حاضر، تاثیر عصاره دانه زغال اخته بر یادگیری و حافظه و برخی پارامترهای سرم در موشهای سوری نر آلزایمری بررسی شد. مواد و روشها: 48 سر موش با وزن تقریبی 25 تا 30 گرم به 6 گروه تقسیم شدند: سالین-سالین، STZ – سالین، STZ- عصاره دانه زغال اخته(25، 50 و 75 میلی گرم بر کیلوگرم) ، سالین-دوز موثر عصاره دانه زغال اخته. جهت ایجاد بیماری آلزایمر از تزریق...
[ 4 ] - Protective effect of curcumin and Curcuma longa extract on apoptosis of motor neurons in cultured spinal cord slices of adult mouse
Introduction: Since Curcuma longa extract and curcumin have been shown to be potent antioxidant agents, they were used in cultured adult mouse spinal cord slices to investigate whether they can inhibit apoptosis in motor neurons. Methods: Slices from the thoracic region of adult mice spinal cord were divided into four groups: 1. Freshlyprepared slices (time 0) 2. Control 3. Slices treated by cu...
[ 5 ] - اثرنانوذرات اکسید روی بربه‌خاطرآوری حافظه، سلول‌های هرمی ناحیه‌ی CA1 هیپوکامپ و برخی فاکتورهای استرس اکسیداتیو در سرم خون رت‌های نر نژاد ویستار
Background & Aims: Due to the fact that nanoscale zinc oxide nanoparticles can pass through the blood brain barrier and have devastating effects on various posts of nervous system, the present study investigated the effects of N-Acetyl cysteine on memory retrieval, hippocampal CA1 pyramidal neurons and some blood serum oxidative stress factors on male Wistar rats treated with zinc oxide nanopar...
[ 6 ] - The Effect of Intra-ventral Tegmental Area Injection of Ghrelin on Morphine-Induced Amnesia in Male Rats: An Experimental Study
Background and Objectives: Extensive evidence shows that morphine impairs cognitive functions. On the other hand, ghrelin is a gastrointestinal hormone that affects learning and memory process. The purpose of the current study was to evaluate the effect of intra-ventral tegmental area (VTA) injection of ghrelin on morphine-induced amnesia in male rats. Materials and Methods: In this experiment...
[ 7 ] - Involvement of Median Septum Region in Ghrelin Effects on Morphine-Induced Memory Impairment in Passive Avoidance Learning
Background and purpose: Many studies have reported the effect of morphine on memory impairment. Evidence suggests that ghrelin enhances memory consolidation. The median septum also has a major role in memory and learning mechanisms. The present study aimed at investigating the role of median septum on the effects of ghrelin in morphine-induced amnesia. Materials and methods: In this experiment...
[ 8 ] - The Role of Middle Septal Ghrelin Receptors in the Effects of Morphine on Memory Consolidation in Passive Avoidance Learning
Introduction: Evidence indicates that morphine impairs memory process. Ghrelin hormone has been linked to learning and memory processes and modulates reward properties of addictive drugs. In this study we examined the role of middle septal ghrelin receptors in the effects of morphine on memory consolidation in passive avoidance learning. Materials & Methods: In this experimental study, 91 ma...
[ 9 ] - The Effect of Intra-Medial Septum Co-Injection of Ghrelin and Nicotine on Morphine Induced Memory Impairment
Evidence indicates that medial septum nicotinic receptors regulate cognitive process. Ghrelin is a gut hormone that regulates energy homeostasis. Ghrelin also is produced in brain and known to be involved in cognitive function. The purpose of the study was to evaluate the effects of medial septal injection of ghrelin on morphine-induced memory impairment in rats. Also, the possible relationship...
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