صحرایی, هدایت
دانشگاه علوم پزشکی بقیه الله
[ 1 ] - تأثیر رایحه‌درمانی با اسطوخودوس بر کیفیت خواب بیماران همودیالیزی (یک کارآزمایی بالینی)
تاریخ دریافت 23/07/1394 تاریخ پذیرش 30/09/1394 چکیده پیش زمینه و هدف: اختلالات خواب از عوارض شایع در بیماران همودیالیزی است که باعث کاهش کیفیت خواب، کیفیت زندگی و افزایش مرگ و میر میشود. با توجه به اینکه در بعضی مطالعات به اثر آرام بخشی گیاه اسطوخودوس اشاره شده است، این پژوهش با هدف تعیین تأثیر رایحه‌درمانی با اسانس گیاه اسطوخودوس بر کیفیت خواب بیماران همودیالیزی انجام شد. مواد و روش‌ها: این ...
[ 2 ] - اثر تغذیه متناوب بر علائم متابولیکی استرس مزمن در موش کوچک آزمایشگاهی نر نژاد NMRI
زمینه و هدف: کاهش کالری (انرژی) دریافتی می‌تواند منجر به مدیریت استرس و بهبود فعالیت دستگاه عصبی شود. در این تحقیق اثر تغذیه متناوب بر علائم متابولیکی استرس مورد بررسی قرار گرفت. روش بررسی: موشهای کوچک آزمایشگاهی نر با میانگین وزنی 3±27 گرم به 4 گروه 7 تایی تقسیم شدند. گروه کنترل آب و غذای کافی دریافت کرده و تحت استرس قرار نگرفتند. گروه دوم (آزمایش) به مدت یک‌هفته و هر روز 2 ساعت از غذ...
[ 3 ] - نقش هسته آکومبانس در پاسخ به استرس مزمن در موش کوچک آزمایشگاهی نر نژاد NMRI
Background and Objectives: Role of different parts of the brain in stress management, especially nucleus accumbens (NAc), is not well known. In this study the role of NAc in response to chronic stress in male mice were evaluated. Materials and Methods: In this experimental study, intra-accumbal uni- and bi-lateral cannulation was performed by stereotaxic instrument. Five minutes before stres...
[ 4 ] - Papaver Rhoeas L. Hydroalcoholic Extract Exacerbates Forced Swimming Test-Induced Depression in Mice
Introduction: Depression is one of the most frequent psychiatric disorders in the world with occurs with higher incidence in women. In the present study, the effect of water-alcoholic extract of Papaver rhoeas L. on forced swimming test (FST) in Swiss-Webster mice were examined. Methods: We used Swiss-Webster mice (20-25 g) to execute FST on them. The plant extract (1, 10, 30, a...
[ 5 ] - Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice
Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate NMDA receptors in the nucleus accumbens in response to chronic stress. Methods: After the unilateral and bilateral cannula placement in the ...
[ 6 ] - The Effects of Fifa 2015 Computer Games on Changes in Cognitive, Hormonal and Brain Waves Functions of Young Men Volunteers
Introduction: Computer games have attracted remarkable attentions in general publics with different cultures and their effects are subject of research by cognitive neuroscientists. In the present study, possible effects of the game Fifa 2015 on cognitive performance, hormonal levels, and electroencephalographic (EEG) signals were evaluated in young male volunteers. Methods: Thirty two subj...
[ 7 ] - Transient inactivation of the central amygdala modulates metabolic and hormonal responses to acute stress in female rats
Introduction: Current study examined the possible role of the central nucleus of amygdala (CeA) transient inactivation on the metabolic and hormonal disturbances induced by acute electro foot shock stress in female rats. Considering the differences between female and male in responses to stress, this study attempts to reveal possible mechanisms underlying these differences. Methods: Uni- or bil...
[ 8 ] - تأثیر تغذیه متناوب بر یادگیری و حافظه فضایی و علایم متابولیکی استرس مزمن در موشهای کوچک آزمایشگاهی نر
Background and Aim: Memory and learning are the putative targets for the stressors by some biochemical reactions such as glucocorticoid hormones. Intermittent feeding is a kind of dietary behavior with some reported positive efficacy on the various systems of the body. The aim of this study was the evaluation of intermittent feeding on learning and spatial memory in the male mice under chronic ...
[ 9 ] - ارزیابی نقش 2-اکسو 4-تیازولیدین-کربوکسیلیک اسید (OTC) بر کسب و بیان وابستگی به مورفین در موشهای نژاد NMRI نر
سابقه و هدف: در طی وابستگی به مورفین غلظت آنتی‌اکسیدان‌های طبیعی کاهش می‌یابد که یکی از مهمترین آنها گلوتاتیون می‌باشد، بنابراین استفاده از آنتی‌اکسیدان‌ها می‌تواند اثرات ترک مورفین را کاهش دهد. لذا، هدف از مطالعه حاضر بررسی اثر دوزهای مختلف 2-اکسو4-تیازولیدین-کربوکسیلیک اسید (OTC = -2-Oxo-4-Thiazolidine-Carboxylic Acid) (فعال کننده آنزیم گلوتاتیون تراسفراز) بر بیان و کسب وابستگی فیزیکی توسط ...
[ 10 ] - The Effect of Saffron Aqueous Extract and Crocin on PTSD Rat Models: The Focus on Learning and Spatial Memory
Background & Objective: Post traumatic stress disorder (PTSD) is an anxiety reaction, which occurs as a result of encountering a seriously traumatic event during one’s lifetime. The aim of this study was to evaluate the effect of saffron aqueous extract and crocin on spatial memory and learning with the Barnes maze in a PTSD model on male Wistar rats (Weighting 200–250 gr). Materials & Method...
[ 11 ] - Changes in Cognitive Functions Following Violent and Football Video Games in Young Male Volunteers by Studying Brain Waves
Introduction: This research investigated the effects of violent and football video games on cognitive functions, cortisol levels, and brain waves. Methods: A total of 64 participants competed in a single-elimination tournament. Saliva samples of all players were obtained before and after the games for the assessment of cortisol levels. The cognitive performances of the players were also assess...
[ 12 ] - Stress-Induced Spatial Memory Deficit Reversed by Basolateral Amygdala NMDA Receptor Inhibition in Male Wistar Rats
Introduction: The present study investigated the role of the Basolateral Amygdala (BLA) N-methyl-D-aspartate (NMDA) receptors in stress-induced spatial memory disturbance among the male Wistar rats. Methods: The male Wistar rats (Average weight =200 g) were cannulated bilaterally in the BLA, and entered the study (n=6-8) after one week. They received seven electro–foot-shock stress sessions o...
[ 13 ] - Involvement of muscarinic system of the dorsal hippocampus on acute stress-induced spatial learning and memory enhancement in male mice
Introduction: The effects of stimulation and inhibition of muscarinic acetylcholine receptors in the dorsal hippocampus on spatial learning and memory in male NMRI mice after acute stress were investigated. Materials and Methods: Animals were divided into two subsets of stress and non-stress. Each subset consisted of: saline, atropine (a muscarinic acetylcholine receptor antagonist) (1, 5, and ...
[ 14 ] - Cognitive Aspects of COVID-19 Pandemic: The Need of “Pandemiology”
COVID-19 spread rapidly worldwide and became a pandemic disease in April 2020. During this period, various medical complications of this disease have been reported, but less attention has been paid to the cognitive aspects caused by the pandemic. In this review article, an attempt has been made to address the cognitive aspects of COVID-19 disease. Importantly, this disease has caused people to ...
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