متاع, علی
مرکز تحقیقات بیوتکنولوژی، دانشگاه علوم پزشکی تبریز، تبریز، ایران
[ 1 ] - بررسی پلی مورفیسم های گیرنده ویتامینD، (BsmI،TaqI) و همراهی آنها با سطح سرمی پروتئین کلوتو در بیماران مبتلا به اسکلرودرمی
Background & Aims: Scleroderma is a chronic connective tissue disease with unknown etiology. Vitamin D, a necessary hormone that plays a particular function in the calcium and phosphate homeostasis, is involved in etiology of this disorder. Klotho, co-receptor of fibroblast growth factor 23 (FGF-23), can interfere in calcium and phosphate metabolism. The purpose of this study was to determ...
[ 2 ] - Combination of metformin and phenformin synergistically inhibits proliferation and hTERT expression in human breast cancer cells
Objective(s): Breast cancer remains a global challenge, and further chemopreventive therapies are still immediately required. Emerging evidence has revealed the potent anti-cancer effects of biguanides, Metformin (MET) and phenformin (PHE). Thus, to explore an efficient chemopreventive strategy for breast cancer, the antiproliferative effects of the combination of MET and PHE against breast can...