طالش ساسانی, سهیلا
دانشگاه گیلان، رشت، ایران
[ 1 ] - بررسی متیلاسیون راه‌انداز p27Kip1 در بیماران مبتلا به کولیت اولسرو
Background & Aims: The CDK inhibitor (CDKI) protein p27kip1 (p27) negatively regulates cyclin D–CDK4 complex in the G1 phase. Alterations in the expression of p27 kip1 cause a degradation of cell growth and promote the development of various diseases. Aberrant methylation patterns have been reported in large number of diseases. The purpose of this study was to investigate the methylation ...
[ 2 ] - اثر سطوح مختلف ورمی کمپوست بر برخی صفات کمی و کیفی گل سوسن هیبرید LA
این تحقیق با هدف بررسی تأثیر سطوح مختلف ورمی‌کمپوست بر ویژگیهای کمی و کیفی گل سوسن (Lilium longiflorum) هیبرید LA رقم Dynamix، در قالب طرح کاملاً تصادفی با پنج تیمار و سه تکرار اجرا شد. تیمارها شامل صفر (تیمار شاهد)، 20، 35، 50 و 65 درصد حجمی ورمی‌کمپوست در بستر کشت حاوی 70 درصد کوکوپیت و 30 درصد پرلیت بود که در شرایط گلخانهای انجام شد. گلهای شاخه بریدنی تیمارهای مختلف پس ...
[ 3 ] - The enhancing effect of electromagnetic field on the expression of Oligodendrocyte transcription factor 1 and 2 (Olig1/2) in the mice cerebral cortex
Olig1 and Olig2, two transcription factors, play regulatory function in the differentiation and specification of oligodendrocyte progenitor cells (OPCs). In this study the effects of electromagnetic fields (EMF) on total protein concentration ( TPC ) and Olig1 and Olig2 expression in the cerebral cortex of mouse was examined. Twenty-one Balb/c mice were separated into three groups: control, EMF...
[ 4 ] - The effect of a VEGFB antagonist peptide on the expression level of miR-210 in a mouse model of breast cancer
Breast cancer is the fourth common cancer worldwide and occurs when breast cells begin to uncontrolled division and tumor formation. Angiogenesis is one of the essential factors in cell growth and maintenance of homeostasis in the natural and pathological conditions, while VEGFs are the most critical factors in angiogenesis. MiR-210 plays an important role in the angiogenesis via association wi...
[ 5 ] - The miR526b-5p-Related Single Nucleotide Polymorphisms, rs72618599, Located in 3\'-UTR of TCF3 Gene, is Associated with the Risk of Breast and Gastric Cancers
Introduction: Single nucleotide polymorphisms result in dysregulation of the proto-oncogene TCF3 gene, which is associated with the development, metastasis, and chemoresistance of different malignancies. Methods: GSE10810 microarray dataset and GEPIA2 online software were used to find differentially expressed genes and the TCF3 status in breast cancer (BC) and gastric cancer (GC), respectively....
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