مهرآیین, فرشته
دانشگاه علوم پزشکی تهران
[ 1 ] - تغییرات فرا ساختاری سلول های شوان و رشته های عصبی گانگلیون های قلب خرگوش پس از تجویز متیل مرکوری
سابقه و هدف: جیوه عنصری سمی است که اولین بار آثار سمی آن در مینیماتای ژاپن در نوزادان مشاهده شد و به نام سندروم مینیماتا خوانده شد. علائم این سندروم لرزش، آتاکسی، پارالیزی و کاهش تون عضلانی است. گانگلیونهای قلبی تنظیم کننده ریتم قلبی هستند که حاوی سلولهای شوان، و رشتههای عصبی میباشند. در این مطالعه تغییرات مورفولوژیک و فراساختاری سلولهای شوان و رشتههای عصبی در این گانگلیونها پس از تاثی...
[ 2 ] - بررسی بیان ژن های GPX3و NRF2 در اووسیتهای موش مدل تخمدان پلی کیستیک تحریک تخمک گذاری شده
Background: One of the common ovary malfunction is polycystic ovary syndrome (PCO). In this study, GPX3 and NRF2 gene experssion which are responsible for oocyte maturation, were studied. Methods: Adult female mice were divided into groups of control, sham, PCO, hyperstimulated control, hyperstimulated sham and hyperstimulated PCO. During two weeks, the weight of all mice and the level of LH a...
[ 3 ] - Antioxidant Role of Oleuropein on Midbrain and Dopaminergic Neurons of Substantia Nigra in Aged Rats
Background: Oleuropein is a phenolic compound which is present in the olive leaf extract. The purpose of the present study was to investigate the neuroprotective effect of oleuropein as an antioxidant agent on the substantia nigra in aged rats. Methods: Twenty 18-month-old Wistar rats (450-550 g) were randomly divided into control and experimental groups. The experimental group received a daily...
[ 4 ] - Neuroprotective Effect of Exogenous Melatonin on Dopaminergic Neurons of the Substantia Nigra in Ovariectomized Rats
Background: Melatonin has receptors in substantia nigra pars compacta (SNc) and regulates development of dopaminergic (DA) neurons. This study was undertaken to determine ability of melatonin to protect SNc dopaminergic neuron loss induced by estrogen deficiency in ovariectomized rats. Methods: Female rats were randomized into four groups of seven each: control, ethanol sham, ovariectomy (ovx) ...
[ 5 ] - Morphological Changes of Rabbit Lacrimal Gland Cells from Amiodarone Administration
Background: Amiodarone is a drug that is used for treatment of cardiac arrhythmia after cardiac ischemia. This drug as b blocker decreases arrhythmia rate but it has many side effects on different tissues. Since there are rare reports about changes of lacrimal glands, this research has been carried out to study the morphological and ultrastructural changes of lacrimal gland cells after amiodaro...
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