فقیهی, فائزه
مرکز تحقیقات سلولی و مولکولی دانشگاه علوم پزشکی ایران، دانشگاه علوم پزشکی ایران، تهران، ایران
[ 1 ] - پتانسیل تمایز شبه عصبی حرکتی سلول های بنیادی خون سازCD133+ و CD34+ مشتق از خون بند ناف انسان؛ در شرایط آزمایشگاه
سابقه و هدف: در این مطالعه، تمایز سلول های بنیادی خون ساز CD133+ و CD34+ مشتق از خون بند ناف انسان، به سلولهای شبه عصبی حرکتی، بررسی شد. روش بررسی: سلولهای بنیادی خون ساز از خون بند ناف انسان جدا شده و سپس، سلولهای CD133+ و CD34+ براساس مارکر، توسط تکنیک جداسازی مغناطیسی MACS تفکیک شدند. بررسی فلوسایتومتری، برای تعیین درصد خلوص سلول های جداشده، انجام گرفت. پس از آن، سلولها در محیط کشت د...
[ 2 ] - Molecular Detection of Anaplasma marginale and Anaplasma ovis (Rickettsiales: Anaplasmataceae) in Ixodid Tick Species in Iran
The present study was conducted as the first molecular detection of Anaplasma species in tick samples based on the sequencing of major surface proteins 4 (msp4) gene fragments in different parts of Iran. A total of 130 tick specimens were collected from Hormozgan, Lorestan, and Guilan, Iran, within 2015 to 2017. Hyalomma asiaticum, Hyalomma dromedarii</em...
[ 3 ] - Differentiation of Mesenchymal Stem Cells Derived From Human Adipose Tissue into Cholinergic-like Cells: In Vitro Study
Introduction: Cholinergic-associated diseases currently constitute a significant cause of neurological and neurodegenerative disabilities. As the drugs are not efficient in improving the suffered tissues, stem cell treatment is considered an effective strategy for substituting the lost cells. Methods: In the current study, we set out to investigate the differentiation properties of human adip...
[ 4 ] - Identification of Fauna of Hard Ticks Collected from Livestock and Molecular Investigation of Coxiella burnetii as Potential Vectors of Q-Fever in South-Khorsan
Background and purpose: Coxiella burnetii infection (causative agent of Q fever) is a public health problem and a zoonotic disease with a global prevalence. The importance of zoonotic diseases and their impact on the health of people in a community is undeniable. The aim of this study was to investigate the prevalence of Coxiella burnetii in hard ticks isolated from livestock in different parts...
[ 5 ] - No Detection of Crimean-Congo Hemorrhagic Fever Virus in Hard Ticks (Ixodidae) from a Highly Endemic Area in Southeast Iran
Introduction: Crimean-Congo Hemorrhagic Fever (CCHF) is a zoonotic viral infection transmitted mainly via CCHF virus-infected ticks between vertebrate hosts. The disease occurs in almost all provinces of Iran. This study investigated the CCHFV infection in hard ticks collected from livestock in the Sistan region of Sistan and Baluchestan Province, southeast of Iran. Methods: In this study, tick...
[ 6 ] - In Vitro Assessment of the Gene Expression of EZH-2 and P300 During Motor Neuron Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells
Introduction: Maintenance of neurogenesis depends on the function of some histone-modifying enzymes; including Enhancer of zeste homolog 2 (EZH2) and histone acetyltransferases (P300). The mechanism of epigenetic regulation and gene expression underlying the transition of human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) into MNs has not been fully clarified. Methods: Two morphoge...
نویسندگان همکار