H Fakhrzadeh

[ 1 ] - Determination of Phenolic Compounds in Pinus eldarica by HPLC

Background: The antioxidant components have been identified in some pine species. Antioxidant properties of proantocyanidins reduce free radicals induced by DNA fragmentation and lipid proxidation and also proanthocyanidines could curb lipid peroxidation. Objective: In this study, we analyzed different parts of Pinus eldarica (bark, seed and needle) and assessed their antioxidant contents. ...

[ 2 ] - Effects of Pinus eldarica Medw. Nut Extract on Blood Glucose and Cholesterol Levels in Hypercholesterolemic Alloxan-induced Diabetic Rats

Background: Diabetes mellitus type 2 with dyslipidemia is a common disease. Previous studies suggest that chemical constituent present in pinus eldarica (P. eldarica) nut posesess antioxidant properties and positively affect glucose metabolism. However blood glucose and cholesterol lowering effects of P. eldarica nut have not been studied so far. Objective: The present study was undertaken to...

[ 3 ] - بیماری‌های قلب و عروق در سالمندان

جمعیت سالمندان ایران به سرعت در حال افزایش است. در حال حاضر بیش از 5 میلیون نفر از ایرانیان در سنین سالمندی به سر می‌برند که بالغ بر 26/7 درصد از جمعیت کشور را تشکیل می‌دهند. تخمین زده می‌شود تا 20 سال آینده جمعیت سالمندان ایران به بیش از 10درصد کل جمعیت کشور خواهد رسید. تغییرات فیزیولوژیک و ساختمانی سیستم قلب و عروق در سالمندی عبارتند از ضخیم‌تر شدن دیواره رگ‌ها، کاهش توان استراحت (relaxation)...

[ 4 ] - تأثیر مکمل اسید چرب امگا 3 بر سندرم متابولیک در سالمندان ساکن آسایشگاه کهریزک: کارآزمایی بالینی دوسو کور

Background: Metabolic syndrome is a cluster of disorders which altogether increase the risk of cardiovascular disease and type 2 Diabetes. We evaluated the effect of consumption of Omega-3 Fatty Acids on different components of this syndrome. Methods: This was a double blind placebo controlled clinical trial on 199 elderly residents of Kahrizak charity foundation in Tehran. Participants were ...

[ 5 ] - ارتباط میان سختی شریانی و وضعیت شناختی در سالمندان

Background: Dementia is a common health problem in the elderly. Studies have shown that levels of pulse wave velocity (PWV) could predict cognitive impairment. The objective of this study was assessment of the relationship between arterial stiffness levels and cognitive status among the older people. Methods: In this cross-sectional study, 60 individuals included 31 women and 29 men aged ≥ 60 ...

[ 6 ] - آدیپونکتین و اختلال عملکرد اندوتلیالی ارزیابی شده توسط اتساع حاصل از جریان خون در بیماران مبتلا به دیابت

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[ 7 ] - ضخامت اینتیما- میدیای کاروتید (CIMT) و اتساع عروقی وابسته به جریان(FMD) در زنان با سابقه قبلی دیابت حاملگی

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[ 8 ] - ارتباط هوموسیستیین با نشانگرهای آترواسکلروز پیش‌بالینی در بیماران مبتلا به دیابت نوع دو و افراد غیردیابتی

Background: The relationship between serum homocysteine levels and cardiovascular diseases has been elucidated since many years ago. In this study, the association between serum levels of homocysteine, folic acid, and vitamin B12 with the pulse wave velocity and Buckberg index or subendocardial viability ratio was assessed in individuals with diabetes and also non-diabetic subjects. Metho...

[ 9 ] - ارتباط آدیپونکتین و نشانگر‌های آتروسکلروز پیش‌بالینی در مبتلایان جدید به دیابت نوع دو: بررسی ضخامت انتیما- میدیای شریان کاروتید و امتیاز کلسیم شریان کرونر

Background: The aim of this study was to assess the association of serum adiponectin and a set of traditional cardiovascular risk factors with carotid artery intimal-medial thickness (CIMT) and coronary artery calcium score (CACS), as markers of subclinical atherosclerosis in subjects with early type 2 diabetes mellitus. Methods: Carotid artery intima- media thickness (measured by B-mode ultrso...

[ 10 ] - بررسی ارتباط بین پرفشاری خون و اختلال شناختی در سالمندان: گزارش کوتاه

Background: Epidemiological studies have reported positive, negative, U-shaped or J-shaped association between high blood pressure and cognitive function as well as dementia whereas other studies have not reported any significant association. The aim of this study was to examine the association between hypertension and cognitive impairment in the elderly residents of Kahrizak Charity Foundation...

[ 11 ] - The Association Between Metabolic Syndrome and Serum Leptin

Objectives: The relation of metabolic syndrome components, insulin resistance and leptin has been studied in elderly women. Methods & Materials: In this cross sectional study, among 225 subjects≥60 year old who were residents of Kahrizak Charity Foundation, 133 (56 men & 77 women) were selected by cluster random sampling. Fasting serum TG, Total Cholesterol, HDL, and leptin levels were measu...

[ 12 ] - Comparison of Waist Circumference and Metabolic Syndrome as a Prognostic Value of Insulin Resistance in Elderly Residents of Kahrizak

Objectives: The aim of this study was to compare of waist circumference with metabolic syndrome ,as a predictor insulin resistance in agroup of elderly population. Methods & Materials: In a cross-sectional study among 225 elderlyaged 60 year old and more whose clinical data were complete, 94 subjects (42 males and 52 females) who were able to sign the consent form Mini Mental stat Examinatio...

[ 13 ] - Is Mini Nutritional Assessment a Good Prognostic Tool of Activities of Daily Living in Ederly?

Objectives: The aims of this study were to investigate the association of Mini-Nutritional Assessment and activities of daily living as well as examining Mini Nutritional Assessment as a good prognostic tool ofactivities of daily living in elderly residents of nursing home. Methods & Materials: In a cross-sectional study, among 1200 recorded files, 247 subjects completed Mini Nutritional Ass...

[ 14 ] - Chronic Kidney Diseases, Metabolic Syndrome and Crp Level in The Elderly Residents of Kahrizak Charity Foundation

Objectives: In this study, we investigated the inter-relationships between C-reactive protein, metabolic syndrome, and chronic kidney disease among a group of Iranian elderly. Methods & Materials: In this cross-sectional study, 122 elderly among 1220 aged residents of Kahrizak Charity foundation with average age of 73.6±9.71 were studied. Metabolic syndrome and chronic kidney diseasewere def...

[ 15 ] - Overweight as a Protective Factor in Dementia Incident in Elderly Residents of Kahrizak Charity Foundation Aged 80 and Older

Objectives: In this study, the relation of late-life body mass index (BMI) and waist circumference with incident dementia risk was investigatedin a group of iranian elderly peopel. Methods & Materials: In cross-sectional present study 107 elderly residents of the Kahrizak Charity Foundation aged 80 and older were participated. Dementia was assessed using Mini-Mental State Examination questio...

[ 16 ] - Effect of Fish Oil on Serum Levels of Lipid Profile, Lipoprotein (a), Apolipoprotein A-1 and B, Fasting Sugar and Insulin, and InsulinResistance in the Elderly Residents of Kahrizak Charity Foundation

Objectives: This study was performed to investigate the effect of ω-3 fatty acids on lipid profiles, lipoprotein (a), apolipoprotein A-1 and apolipoprotein B, fasting glucose and insulin, and insulin resistance in a group of Iranian elderly subjects. Methods & Materials: In this clinical trial, 124 elderly residents of the KahrizakCharity Foundation, aged 65 and older were divided into two i...

[ 17 ] - The Relationship Between Mental State and Functional Status in Elderly Residents of Kahrizak

Objectives: The current study was performed to investigate the relationship between mental impairment and each component of activity of daily living (ADL) in elderly residents of the Kahrizak Charity Foundation. Methods & Materials: Standardized Iranian Mini Mental examination and Barthel index were used to assest cognitive status and ADL in 184 elderly residents of Kahrizak, respectively. ...

[ 18 ] - Prevalence of Hypertension and Diabetes in Elderly Residents of Kahrizak

Objectives: The aim of the present study was to investigate the prevalence of hypertension and type II diabetes in elderly Iranianresidents of the Kahrizak Charity Foundation (KCF). Methods & Materials: In this cross-sectional study, a total of two hundred sixty eight men and women ≥60 years were studied. The data were collected during annual health examination of the elderly residents in KC...

[ 19 ] - The Role of Intestinal Microbiota in Cognitive Disorders

Cognitive disorders are one of the major public health issues in older population worldwide. Problems in forming and storing new memories, short-term memory impairment, and other cognitive problems are common symptoms of cognitive disorders that have no definite treatment yet. Recent studies have shown an association between gut microbiota and cognitive impairments described as microbiota-gut-...

[ 20 ] - ELDERLY STUDIES AT THE INSTITUTE OF ENDOCRINE AND METABOLIC SCIENCES

Background: Identifying the risk factors for the health of the elderly and designing interventions to improve the health of the elderly is one of the priorities of the health care system in the world today. This first requires the promotion of scientific knowledge in the field of health problems of the elderly. Methods: In this review conducted in 1399, all studies with the keyword of aging or...