Eveline Vandenwinckel

[ 1 ] - Synthesis and Photosensitizing Properties of an Activatable Phthalocyanine-Subphthalocyanine Triad

In this article, we describe a photosensitizer (PS) whose ability to generate singlet oxygen (1O2) and fluorescence emission has been designed as tumor responsive. More specifically, the PS consists of a silicon phthalocyanine (SiPc) core, axially substituted with two subphthalocyanine (SubPc) units, covalently linked by a disulfide linker, which is cleavable in the presence of a strong reducin...