Masoud Karimi Goftar

[ 1 ] - Topoisomerase Inhibitors and Types of Them

Objective: In this paper, we have introduced topoisomerase inhibitors, mechanism of action and types of them. DNA topoisomerases are ubiquitous enzymes that catalyze essential enzymes to solve the topological problems accompanying key nuclear processes such as DNA replication, transcription, repair and chromatin assembly by introducing temporary single or double strand breaks in the DNA. Result...

[ 2 ] - Thermodynamic Characterization of the Aggregation Phenomena of Safranine‌T by Spectral Titration and Chemometric Analysis

The dimerization constants of Safranine T have been determined by studying the dependence of its absorption spectra on the temperature in the range 30–70 ◦C at different total concentrations of Safranine T (1.03×10−5, 1.44×10−5 and 1.73×10−5 M). The monomer–dimer equilibrium of Safranine T has been determined by applying MCR-ALS method on the absorpti...

[ 3 ] - Licorice (Glycyrrhiza Glabra Linn) as a Valuable Medicinal Plant

Glycyrrhiza glabra, family Leguminoseae, is a plant which grows in Egypt and other countries of the world. Its roots possess some nutritive value and medicinal properties. Glycyrrhiza glabra Linn, a commonly used herb in ayurvedic medicine. Studies indicate that Glycyrrhiza glabra Linn possesses antibacterial, antioxidant, antimalerial, antispasmodic, anti-inflammatory and anti hype...

[ 4 ] - Topoisomerase Inhibitors and Types of Them

Objective: In this paper, we have introduced topoisomerase inhibitors, mechanism of action and types of them. DNA topoisomerases are ubiquitous enzymes that catalyze essential enzymes to solve the topological problems accompanying key nuclear processes such as DNA replication, transcription, repair and chromatin assembly by introducing temporary single or double strand breaks in the DNA. Result...

[ 5 ] - Thermodynamic Characterization of the Aggregation Phenomena of Safranine‌T by Spectral Titration and Chemometric Analysis

The dimerization constants of Safranine T have been determined by studying the dependence of its absorption spectra on the temperature in the range 30–70 ◦C at different total concentrations of Safranine T (1.03×10−5, 1.44×10−5 and 1.73×10−5 M). The monomer–dimer equilibrium of Safranine T has been determined by applying MCR-ALS method on the absorpti...

[ 6 ] - Licorice (Glycyrrhiza Glabra Linn) as a Valuable Medicinal Plant

Glycyrrhiza glabra, family Leguminoseae, is a plant which grows in Egypt and other countries of the world. Its roots possess some nutritive value and medicinal properties. Glycyrrhiza glabra Linn, a commonly used herb in ayurvedic medicine. Studies indicate that Glycyrrhiza glabra Linn possesses antibacterial, antioxidant, antimalerial, antispasmodic, anti-inflammatory and anti hype...