Vahideh Zakeri

[ 1 ] - Preparation, characterization and transfection efficiency of nanoparticles composed of alkane-modified polyallylamine

Objective(s): Although viral vectors are considered efficient gene transfer agents, their board application has been limited by toxicity, immunogenicity, mutagenicity and small gene carrying capacity. Non-viral vectors are safe but they suffer from low transfection efficiency. In the present study, polyallylamine (PAA) in two molecular weights (15 and 65 kDa) was modified by alkane derivatives ...