Majid Yavarian

Shiraz Nephro-Urology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

[ 1 ] - Pharmacogenetic variation of SLC47A1 gene and metformin response in type2 diabetes patients

Type 2 diabetes mellitus is a worldwide epidemic disorder with considerable health and economic consequences. Metformin is one of the most commonly prescribed oral antidiabetic drugs. Pharmacogenetic studies showed that variants in genes related to the pharmacokinetics of metformin were associated with glucose-lowering effect of metformin. The aim of this study was to evaluate pharmacogenetic v...

[ 2 ] - نقش پلی‌مورفیسم‌rs7895833 SIRT-1 در استعداد ابتلا به سندروم تخمدان پلی‌کیستیک

Introduction: Sirtuin 1 is a protein deacetylase that plays an important role in many cellular processes. The serum sirtuin 1 levels are higher in the polycystic ovary syndrome (PCOS) patients than the healthy subjects. The aim of this study was to assess the role of SIRT-1 rs7895833 polymorphism in the susceptibility of PCOS. Methods: This case-control study was done on 456 Iranian women fr...

نویسندگان همکار